Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.49 |
| ▸ | BRD4 | O60885 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211927 | 0.87 | MAPT (0.50) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL8732802 | 0.83 | MAPT (0.46) | PTGER1BRD4MAPTMAPK1TDP1 | |
| SCHEMBL8074754 | 0.82 | MCL1 (0.51) | MAPTTDP1L3MBTL1IDO1HTR1A | |
| SCHEMBL26013299 | 0.81 | MAPT (0.63) | PTGER1BRD4MAPTMAPK1TDP1 | |
| SCHEMBL10798688 | 0.78 | PTGER1 (0.42) | PTGER1BRD4MAPTMAPK1TDP1 | |
| SCHEMBL3731514 | 0.78 | BRD4 (0.48) | PTGER1BRD4MAPTMAPK1TDP1 | |
| SCHEMBL920470 | 0.77 | ALDH1A1 (0.50) | MAPTIDO1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL28239249 | 0.76 | MAPT (0.44) | MAPTMAPK1TDP1L3MBTL1HTR1A | |
| SCHEMBL1190605 | 0.75 | MAPT (0.52) | BRD4MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL11739704 | 0.75 | APP (0.44) | MAPK1TDP1L3MBTL1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |