Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719 | 0.97 | TSHR (0.39) | TSHRACHELMNAALOX12ALDH1A1 | |
| Fluoride SCHEMBL27639908 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27938609 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL28099522 | 0.88 | LMNA (0.33) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL55165 | 0.76 | — | — | |
| SCHEMBL7631451 | 0.76 | TSHR (0.39) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL8992490 | 0.75 | ALDH1A1 (0.54) | TSHRALDH1A1TP53CA1CA2 | |
| SCHEMBL22607984 | 0.73 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL28763766 | 0.73 | — | — | |
| SCHEMBL31469567 | 0.73 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864432-A | A kind of preparation method and applications of the poly bis phenyl methyl silazane of methyl blocking | 湖北新海鸿化工有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108715738-A | A kind of high temperature resistant LED high transparency organic silica gels | 湖北新海鸿化工有限公司 | 2018-10-30 | — | — | CN | disclosed |
| CN-108641672-A | A kind of anti-oxidant LED packaging plastics of high transparency | 湖北新海鸿化工有限公司 | 2018-10-12 | — | — | CN | disclosed |
| CN-108587454-A | A kind of anti-aging saturating organic silica gel of height of high temperature resistant | 湖北新海鸿化工有限公司 | 2018-09-28 | — | — | CN | disclosed |