SCHEMBL8719

SCHEMBL8719

C[Si](c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
ACHE P22303 2/20 0.39
LMNA P02545 1/20 0.39
ALOX12 P18054 1/20 0.39
ALDH1A1 P00352 2/20 0.35
ORAI1 Q96D31 2/20 0.33
ORAI2 Q96SN7 2/20 0.33
ORAI3 Q9BRQ5 2/20 0.33
TRPV6 Q9H1D0 2/20 0.33
CA4 P22748 2/20 0.33
TP53 P04637 1/20 0.33
PCSK9 Q8NBP7 1/20 0.33
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA9 Q16790 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
CA12 O43570 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27938609 0.97 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
Ammonia Solution, Strong SCHEMBL28239369 0.97 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
Fluoride SCHEMBL27639908 0.97 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL28099522 0.91 LMNA (0.33) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL55165 0.79
SCHEMBL7631451 0.79 TSHR (0.39) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL8992490 0.78 ALDH1A1 (0.54) TSHRALDH1A1TP53CA1CA2
SCHEMBL31469567 0.76 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL22607984 0.76 TSHR (0.37) TSHRACHELMNAALOX12ALDH1A1
SCHEMBL28763766 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15083 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120056555-A Double-channel prefabricated occluding lap joint waterproof coiled material and preparation method thereof 河北宇阳泽丽防水材料有限公司 2025-05-30 CN claimed
CN-119570360-A Large-thickness ultralow-density high-toughness silicon rubber heat-resistant coating and preparation method and application thereof 航天材料及工艺研究所 2025-03-07 CN claimed
CN-116003460-B Method for synthesizing optical active organosilicon compound by asymmetric conjugate addition 河南师范大学 2025-02-07 CN claimed
CN-116425760-B Synthesis method of chiral (-) -cephalotaxine, intermediate and analogue thereof 兰州大学 2024-11-26 CN claimed
EP-3930868-B1 COATED FLOW PATH COMPONENTS FOR CHROMATOGRAPHIC EFFECTS WATERS TECHNOLOGIES CORP (US) 2024-07-17 EP claimed
CN-118324823-A Heterofluorene rare earth compound, preparation method thereof and application thereof in olefin polymerization 中国科学院长春应用化学研究所 2024-07-12 CN claimed
WO-2024140294-A1 ORGANIC COMPOUND AND APPLICATION THEREOF IN OLED DEVICE 北京云基科技股份有限公司 2024-07-04 WO claimed
EP-4373831-A1 PROCESSES FOR THE PREPARATION OF ESTETROL AND INTERMEDIATES THEREOF Newchem S.p.A. (IT) 2024-05-29 EP claimed
US-20240150390-A1 NOVEL METHOD FOR PRODUCING ANTIBODY-IMMUNOSTIMULATOR CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-05-09 US claimed
CN-117903435-A MQ resin type silicon rubber damping additive and preparation method and application thereof 山东大学 2024-04-19 CN claimed
EP-0405461-A2 Silicone-based composite rubber composition and uses thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-01-02 EP claimed
US-4942202-A A CROSSLINKABLE SILICONE RUBBER, A SATURATED ELASTOMER THAT WILL NOT CROSSLINK WITH PEROXIDE AND A POSSIBLE THIRD ELASTOMER THAT WILL CROSSLINK JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-07-17 US claimed
US-4863916-A BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1989-09-05 US claimed
US-4840946-A Benzazolythio-carbapenem antibiotics BAYER AKTIENGESELLSCHAFT (DE) 1989-06-20 US claimed
EP-0268963-A1 Benzazolylthio-carbapenem antibiotics BAYER AG (DE) 1988-06-01 EP claimed
EP-0247431-A1 Substituted 6-hydroxymethylcarbapenem antibiotics, process for their preparation and their use BAYER AG (DE) 1987-12-02 EP claimed
EP-0174561-A1 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives HOECHST UK LIMITED (GB) 1986-03-19 EP claimed
US-4508911-A Amine intermediates for analgesic compounds THE UPJOHN COMPANY (US) 1985-04-02 US claimed
US-3980803-A Linear phenylmethylsilicone oil as dielectric for stationary electric device TOKYO SHIBAURA ELECTRIC CO., LTD. (JA) 1976-09-14 US claimed
US-3943157-A Synthesis of codling moth attractant ZOECON CORPORATION (US) 1976-03-09 US claimed