SCHEMBL28239392

SCHEMBL28239392

CC(Cc1ccccc1)C(=O)ON

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRR Q9GZT4 2/20 0.53
HPGD P15428 1/20 0.51
CYP3A4 P08684 2/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
ALPI P09923 1/20 0.48
PKM P14618 1/20 0.48
PTGS1 P23219 1/20 0.48
XIAP P98170 1/20 0.48
SLC7A5 Q01650 1/20 0.48
SLC6A2 P23975 2/20 0.48
TAAR1 Q96RJ0 2/20 0.48
MAOA P21397 1/20 0.48
SLC6A4 P31645 1/20 0.48
SLC6A3 Q01959 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
CYP2A6 P11509 1/20 0.48
ADORA2A P29274 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28221964 0.98 SRR (0.54) SRRHPGDCYP3A4TSHRMAPK1
SCHEMBL28799585 0.84 AGXT (0.42) HPGDNPC1RAB9AKMT2A
SCHEMBL17761604 0.83 ALDH1A1 (0.60) HPGDCYP3A4TSHRMAPK1NPC1
SCHEMBL2600694 0.83 ALDH1A1 (0.60) HPGDCYP3A4TSHRMAPK1NPC1
SCHEMBL517463 0.83 ALDH1A1 (0.60) HPGDCYP3A4TSHRMAPK1NPC1
SCHEMBL265561 0.81 ALDH1A1 (0.58) HPGDCYP3A4TSHRMAPK1NPC1
SCHEMBL12764099 0.81 ALDH1A1 (0.58) HPGDCYP3A4TSHRMAPK1NPC1
Ammonia Solution, Strong SCHEMBL9995407 0.81 ALDH1A1 (0.59) HPGDCYP3A4TSHRMAPK1NPC1
SCHEMBL265176 0.81 ALDH1A1 (0.58) HPGDCYP3A4TSHRMAPK1NPC1
SCHEMBL27583798 0.81 HPGD (0.51) SRRHPGDCYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108463219-A I L-8 inhibitor for use in the treatment of chemotherapy-induced peripheral neuropathy 东佩制药股份公司 2018-08-28 CN claimed