Chlorobenzene

Chlorobenzene

SCHEMBL28239447

CCN=C=O.Clc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
CYP1A2 P05177 1/20 0.34
TACR1 P25103 1/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
G6PC1 P35575 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
BCHE P06276 1/20 0.32
CNR1 P21554 2/20 0.32
CNR2 P34972 2/20 0.32
PYCR1 P32322 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL22121584 0.83 ALDH1A1 (0.41) TSHRGABRA1GABRB2CYP1A2ALDH1A1
Benzene SCHEMBL11866495 0.82 GABRA1 (0.36) TSHRGABRA1GABRB2
Benzene SCHEMBL28293157 0.82 GABRA1 (0.36) TSHRGABRA1GABRB2
Toluene SCHEMBL27586261 0.81 LMNA (0.48) TSHRGABRA1GABRB2ALDH1A1LMNA
Fluorobenzene SCHEMBL28129393 0.79 GABRA1 (0.35) TSHRGABRA1GABRB2CYP1A2ALDH1A1
Chlorobenzene SCHEMBL28864453 0.79 MIF (0.47) TSHRGABRA1GABRB2ALDH1A1
SCHEMBL17961601 0.78 CYP3A4 (0.45) TSHRGABRA1GABRB2CYP1A2ALDH1A1
Benzoic Acid SCHEMBL1457713 0.76 TSHR (0.54) TSHRCYP1A2ALDH1A1LMNACES2
SCHEMBL11195442 0.75 HRH3 (0.38) TSHRGABRA1GABRB2CYP1A2ALDH1A1
Phenethyl Isocyanate SCHEMBL5082513 0.75 MIF (0.53) TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115335425-B Method for preparing low haze polymer compositions for high refractive index optical materials PPG工业俄亥俄公司 2023-10-24 CN disclosed
CN-115335425-A Process for preparing low haze polymer compositions for high refractive index optical materials PPG工业俄亥俄公司 2022-11-11 CN disclosed
CN-108368068-A Amino Zole derivatives 帝人制药株式会社 2018-08-03 CN disclosed