SCHEMBL28239605

SCHEMBL28239605

CN(C)C1CCC(CC2(O)CCCCC2)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.34
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4752092 0.85 CYP2C19 (0.39) HSD11B1CYP2C19
SCHEMBL11270734 0.78 CYP2C19 (0.35) CYP2C19
SCHEMBL11124526 0.72 CYP2C19 (0.34) CYP2C19
SCHEMBL11126900 0.69 SLC6A1 (0.32) CYP2C19
SCHEMBL6366799 0.69 SIGMAR1 (0.38)
SCHEMBL10325573 0.68 ESR1 (0.34)
SCHEMBL1989889 0.68 ESR1 (0.34)
SCHEMBL1989890 0.68 ESR1 (0.34)
SCHEMBL152273 0.67 TDP1 (0.32)
SCHEMBL18844890 0.66 ADH1C (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108503555-A 4- ((4- (dimethylamino) cyclohexyl) methyl) cyclohexanol and preparation method and application 万华化学集团股份有限公司 2018-09-07 CN claimed
CN-108503555-A 4- ((4- (dimethylamino) cyclohexyl) methyl) cyclohexanol and preparation method and application 万华化学集团股份有限公司 2018-09-07 CN disclosed
CN-108503555-A 4- ((4- (dimethylamino) cyclohexyl) methyl) cyclohexanol and preparation method and application 万华化学集团股份有限公司 2018-09-07 CN disclosed