Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28983001 | 0.83 | HPGD (0.61) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| SCHEMBL18893131 | 0.82 | L3MBTL1 (0.74) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| SCHEMBL30848409 | 0.81 | HPGD (0.64) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| SCHEMBL8029750 | 0.79 | HPGD (0.69) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| SCHEMBL24801412 | 0.78 | HPGD (0.68) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| SCHEMBL24568217 | 0.78 | HPGD (0.68) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| Alcohol SCHEMBL6836623 | 0.78 | L3MBTL1 (0.68) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| SCHEMBL528651 | 0.76 | CTSD (0.68) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| SCHEMBL2251625 | 0.76 | HPGD (0.70) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 | |
| SCHEMBL2251629 | 0.76 | HPGD (0.70) | HPGDALDH1A1CTSDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108431007-A | PYRAZOLOPYRIMIDINE DERIVATIVES AS BTK INHIBITORS FOR THE TREATMENT OF CANCER | 洛克索肿瘤学股份有限公司 | 2018-08-21 | — | — | CN | disclosed |