Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993233 | 0.89 | CES2 (0.50) | LMNAKMT2ACES2CES1SCN1A | |
| SCHEMBL27500253 | 0.85 | KMT2A (0.50) | LMNAKMT2ACES2CES1SCN1A | |
| SCHEMBL28239732 | 0.83 | RXFP1 (0.50) | HTR1ASLC6A2SLC6A3CHRM3CES2 | |
| SCHEMBL7408465 | 0.81 | KMT2A (0.47) | LMNAKMT2ACES2CES1SCN1A | |
| SCHEMBL28315283 | 0.81 | SCN1A (0.45) | SLC6A2SLC6A3KMT2ACHRM3SLC6A4 | |
| SCHEMBL28240607 | 0.80 | MEN1 (0.59) | KMT2ACHRM3SCN1ASCN2ASCN3A | |
| SCHEMBL28011429 | 0.79 | SCN1A (0.52) | SLC6A2SLC6A3KMT2ACHRM3SLC6A4 | |
| SCHEMBL1912949 | 0.77 | CHRNA7 (0.61) | KMT2ACHRM3SCN1ASCN2ASCN3A | |
| SCHEMBL29003856 | 0.77 | SLC6A2 (0.53) | SLC6A2SLC6A3KMT2ASLC6A4SCN1A | |
| Methylene Chloride SCHEMBL29003874 | 0.76 | MEN1 (0.54) | KMT2ACHRM3SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108456204-B | Benzothiazine derivative, and preparation method and application thereof | 四川大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-108456204-A | Benzothiazine derivative and its preparation method and application | 四川大学 | 2018-08-28 | — | — | CN | disclosed |