Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 4/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27500253 | 0.93 | KMT2A (0.50) | CES2CES1KMT2ALMNAALDH1A1 | |
| SCHEMBL7408465 | 0.89 | KMT2A (0.47) | CES2CES1KMT2ALMNAALDH1A1 | |
| SCHEMBL28239805 | 0.89 | HTR1A (0.50) | CES2CES1KMT2ALMNAALDH1A1 | |
| SCHEMBL208341 | 0.86 | TSHR (0.53) | KMT2ALMNAALDH1A1SCN1ASCN2A | |
| SCHEMBL16552873 | 0.86 | CES2 (0.53) | CES2CES1KMT2ALMNAALDH1A1 | |
| SCHEMBL16669555 | 0.84 | KMT2A (0.41) | CES2CES1KMT2ALMNAALDH1A1 | |
| SCHEMBL16669554 | 0.84 | KMT2A (0.41) | CES2CES1KMT2ALMNAALDH1A1 | |
| SCHEMBL5789103 | 0.80 | HTR3A (0.66) | LMNASMN1; SMN2 | |
| SCHEMBL5789101 | 0.80 | HTR3A (0.66) | LMNASMN1; SMN2 | |
| SCHEMBL8551876 | 0.80 | BCHE (0.58) | KMT2ASCN1ASCN2ASCN3AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659882-B | High-flame-retardance long-service-life thermoplastic polyolefin waterproof coiled material and preparation method thereof | 北京宇阳泽丽防水材料有限责任公司 | 2024-06-11 | — | — | CN | claimed |
| CN-117659882-B | High-flame-retardance long-service-life thermoplastic polyolefin waterproof coiled material and preparation method thereof | 北京宇阳泽丽防水材料有限责任公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117659882-A | High-flame-retardance long-service-life thermoplastic polyolefin waterproof coiled material and preparation method thereof | 北京宇阳泽丽防水材料有限责任公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-107835805-A | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2018-03-23 | — | — | CN | disclosed |
| WO-2016079669-A1 | LABELED AMINO PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2016-05-26 | — | — | WO | disclosed |
| EP-2855428-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | Genentech, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177224-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | GENENTECH, INC. (US) | 2013-11-28 | — | — | WO | disclosed |
| WO-2000021910-A2 | 1,2-DISUBSTITUTED CYCLOPROPANES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2000-04-20 | — | — | WO | disclosed |