Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 7/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 7/20 | 0.61 |
| ▸ | HTR1D | P28221 | 6/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | HTR1B | P28222 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2536283 | 0.85 | GAA (0.67) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL31660992 | 0.85 | GAA (0.67) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL32669329 | 0.83 | TRPM8 (0.67) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL6948769 | 0.82 | HTR2A (0.67) | TRPM8MAPTHTR1DHTR1AHTR1B | |
| SCHEMBL17525726 | 0.79 | GAA (0.66) | KDM4EMAPTHTR1DSLC6A4HTR1A | |
| SCHEMBL2825796 | 0.78 | RAB9A (0.70) | KDM4EMAPTHTR1DHTR1AHTR1B | |
| SCHEMBL6988545 | 0.77 | HTR1D (0.78) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL6388022 | 0.77 | POLB (0.78) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| 5-Benzyloxytryptamine SCHEMBL29785061 | 0.77 | TRPM8 (1.00) | TRPM8KDM4EMAPTLTA4HPLA2G2A | |
| SCHEMBL27406721 | 0.77 | TRPM8 (0.77) | TRPM8KDM4EMAPTLTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020179-B9 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHESTVO OTECHESTVENNYE LEKARSTVA (RU) | 2011-02-02 | — | — | EP | disclosed |
| EP-1020179-B1 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHEST (RU) | 2009-12-09 | — | — | EP | disclosed |