Propionic Acid

Propionic Acid

SCHEMBL28240809

CC(C)N1CCNCC1.CCC(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.41
CHRM5 P08912 1/20 0.41
CHRM3 P20309 1/20 0.41
FFAR3 O14843 1/20 0.40
OPRD1 P41143 11/20 0.39
OPRM1 P35372 5/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
CA2 P00918 1/20 0.36
CHKA P35790 1/20 0.36
OPRK1 P41145 2/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
CHRNB3 Q05901 1/20 0.35
CHRNA6 Q15825 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecanoate SCHEMBL29052356 0.81 GPR84 (0.53)
Fumaric Acid SCHEMBL7491655 0.80 KDM4E (0.38) SIGMAR1CHRM5CHRM3OPRD1
Fumaric Acid SCHEMBL7491648 0.80 KDM4E (0.38) SIGMAR1CHRM5CHRM3OPRD1
SCHEMBL5387 0.80
SCHEMBL77101 0.80
SCHEMBL1706403 0.80 MEN1 (0.39) SIGMAR1CHRM5CHRM3OPRD1SLC6A2
Acetamide SCHEMBL4168128 0.79 OPRD1 (0.39) SIGMAR1CHRM5CHRM3OPRD1SLC6A4
Benzene SCHEMBL27485207 0.78 MEN1 (0.50) SIGMAR1OPRD1SLC6A2SLC6A4
SCHEMBL13509549 0.78 MEN1 (0.38) SIGMAR1CHRM5CHRM3SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL522550 0.78 MEN1 (0.38) SIGMAR1CHRM5CHRM3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103857440-B Antimycotic and antibacterium prodrug based on conjugate 维奥姆生物科学有限公司 2018-09-25 CN disclosed