Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Mercaptobenzothiazole SCHEMBL9414126 | 0.86 | MAPT (0.54) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL9414129 | 0.84 | RAB9A (0.51) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL9132603 | 0.79 | MAPT (0.56) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL3789760 | 0.79 | ALDH1A1 (0.54) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL29509878 | 0.79 | ALDH1A1 (0.54) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL23237 | 0.79 | ALDH1A1 (0.54) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL27478298 | 0.77 | ALDH1A1 (0.48) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL10945293 | 0.77 | ALDH1A1 (0.52) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL7207521 | 0.77 | ALDH1A1 (0.52) | NPC1RAB9AMAPTKMT2AALDH1A1 | |
| 2-Mercaptobenzothiazole SCHEMBL57787 | 0.77 | ALDH1A1 (0.52) | NPC1RAB9AMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108559150-A | A kind of soft high strength white butyl adhesive plaster rubber and its preparation method and application | 湖北华强科技有限责任公司 | 2018-09-21 | — | — | CN | disclosed |