Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403666 | 0.78 | RAB9A (0.59) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL16863150 | 0.77 | MAOA (0.50) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL8408030 | 0.77 | NPC1 (0.58) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL28044570 | 0.76 | NPC1 (0.64) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL27625488 | 0.76 | MMP2 (0.67) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL31320649 | 0.73 | MMP2 (0.64) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL4927452 | 0.73 | MMP2 (0.64) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL3009674 | 0.73 | HPGD (0.59) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL7537576 | 0.73 | MMP2 (0.72) | MMP2MMP9ADAM17NPC1RAB9A | |
| SCHEMBL13612673 | 0.72 | MAOA (0.61) | MMP2MMP9ADAM17NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558843-A | A kind of cumarin-triazole-isatin type compound and its preparation method and application | 贵州医科大学 | 2018-09-21 | — | — | CN | claimed |
| CN-108558843-A | A kind of cumarin-triazole-isatin type compound and its preparation method and application | 贵州医科大学 | 2018-09-21 | — | — | CN | disclosed |