Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19029928 | 0.79 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL30090141 | 0.79 | IRAK4 (0.51) | IRAK4 | |
| SCHEMBL19030045 | 0.74 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL19045997 | 0.74 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL24206625 | 0.71 | GAA (0.57) | — | |
| SCHEMBL14747899 | 0.69 | ADRB1 (0.42) | — | |
| SCHEMBL30066216 | 0.68 | ADRB1 (0.41) | — | |
| SCHEMBL24670695 | 0.68 | ADRB1 (0.41) | — | |
| SCHEMBL19045021 | 0.68 | IRAK4 (0.42) | IRAK4 | |
| SCHEMBL10974562 | 0.66 | CYP2D6 (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473498-A | Pyrazolo [1,5a] pyrimidine derivatives as IRAK4 conditioning agents | 豪夫迈·罗氏有限公司 | 2018-08-31 | — | — | CN | disclosed |