Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 8/20 | 0.65 |
| ▸ | FABP5 | Q01469 | 7/20 | 0.65 |
| ▸ | FABP3 | P05413 | 5/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | MAP2 | P11137 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14916995 | 0.85 | FABP4 (0.80) | FABP4FABP5FABP3CYP2C9NPSR1 | |
| SCHEMBL2820951 | 0.84 | FABP4 (0.82) | FABP4FABP5FABP3NPSR1KDM4E | |
| SCHEMBL14917210 | 0.81 | FABP4 (0.67) | FABP4FABP5FABP3CYP2C9NPSR1 | |
| SCHEMBL14916408 | 0.79 | FABP4 (1.00) | FABP4FABP5FABP3CYP2C9NPSR1 | |
| SCHEMBL14917028 | 0.79 | FABP4 (0.69) | FABP4FABP5FABP3CYP2C9NPSR1 | |
| SCHEMBL14916660 | 0.79 | FABP4 (0.62) | FABP4FABP5FABP3CYP2C9NPSR1 | |
| SCHEMBL14916906 | 0.79 | FABP4 (0.61) | FABP4FABP5FABP3CYP2C9NPSR1 | |
| SCHEMBL14917296 | 0.79 | FABP4 (0.58) | FABP4FABP5FABP3CYP2C9NPSR1 | |
| SCHEMBL21083000 | 0.77 | FABP4 (1.00) | FABP4FABP5FABP3CYP2C9NPSR1 | |
| SCHEMBL2824339 | 0.77 | FABP4 (0.51) | FABP4FABP5FABP3CYP2C9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809605-B1 | QUINOLINES AS ALLOSTERIC ENHANCERS OF THE GABA-B RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-11 | — | — | EP | claimed |