Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 5/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820954 | 0.84 | ALDH1A1 (0.54) | FABP4FABP5DHODHALDH1A1KDM4E | |
| SCHEMBL14917386 | 0.79 | FABP4 (0.79) | FABP4FABP5DHODHALDH1A1KDM4E | |
| SCHEMBL14916313 | 0.77 | FABP4 (0.54) | FABP4FABP5ALDH1A1KDM4ELMNA | |
| SCHEMBL2824337 | 0.77 | FABP4 (0.65) | FABP4FABP5DHODHALDH1A1KDM4E | |
| SCHEMBL14932748 | 0.73 | ALDH1A1 (0.48) | FABP4FABP5ALDH1A1KDM4ELMNA | |
| SCHEMBL2829190 | 0.72 | HAVCR2 (0.55) | DHODHALDH1A1HSD17B10CYP2C9CYP3A4 | |
| SCHEMBL28112715 | 0.72 | FABP4 (0.65) | FABP4FABP5DHODHLMNAFABP3 | |
| SCHEMBL24122352 | 0.70 | DHODH (0.71) | FABP4FABP5DHODHLMNATSHR | |
| SCHEMBL2826055 | 0.70 | ALDH1A1 (0.56) | FABP4ALDH1A1KDM4ELMNAHSD17B10 | |
| SCHEMBL2823585 | 0.68 | ALDH1A1 (0.61) | FABP4ALDH1A1KDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809605-B1 | QUINOLINES AS ALLOSTERIC ENHANCERS OF THE GABA-B RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-11 | — | — | EP | claimed |