SCHEMBL28243748

SCHEMBL28243748

c1ccc(Cc2cc(-c3ccncc3)ccn2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.48
FYN P06241 1/20 0.48
PRMT6 Q96LA8 1/20 0.47
PRKCI P41743 1/20 0.47
S1PR1 P21453 1/20 0.44
PIK3CA P42336 1/20 0.44
GSK3B P49841 2/20 0.43
HTR6 P50406 1/20 0.43
CYP11B1 P15538 4/20 0.42
CYP11B2 P19099 4/20 0.42
CYP17A1 P05093 3/20 0.42
CYP3A4 P08684 3/20 0.42
CYP19A1 P11511 2/20 0.42
HRH3 Q9Y5N1 1/20 0.42
KDR P35968 1/20 0.42
GRK2 P25098 1/20 0.42
LTA4H P09960 1/20 0.41
PRKACA P17612 1/20 0.41
CDK8 P49336 1/20 0.41
CLK2 P49760 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL30008835 0.98 FYN (0.47) NOTUMFYNPRMT6PRKCIS1PR1
SCHEMBL28133235 0.83 CYP17A1 (0.42) FYNPRMT6PRKCICYP11B1CYP11B2
SCHEMBL28135607 0.82 L3MBTL1 (0.42) FYNS1PR1GSK3B
Hydrochloric Acid SCHEMBL28477394 0.81 CYP17A1 (0.41) FYNPRMT6PRKCICYP11B1CYP11B2
SCHEMBL28486374 0.81 CYP17A1 (0.48) GSK3BCYP11B1CYP11B2CYP17A1CYP3A4
Hydrochloric Acid SCHEMBL28404833 0.80 CYP17A1 (0.47) GSK3BCYP11B1CYP11B2CYP17A1CYP3A4
SCHEMBL28488403 0.79 CYP17A1 (0.40) FYNPRMT6PRKCICYP11B1CYP11B2
SCHEMBL20197185 0.78 CCNC (0.43) FYNGSK3BLTA4HCDK8GSK3A
SCHEMBL5115091 0.74 RECQL (0.50) FYNPRKCI
SCHEMBL13562418 0.74 NOS2 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110642778-B Viologen compound, preparation method and application thereof 淮阴师范学院 2022-10-04 CN disclosed
CN-108474988-A Electrochromic compositions and use its electrochromic device 伊格拉斯科技有限公司 2018-08-31 CN disclosed