Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.44 |
| ▸ | WNT3A | P56704 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzofuran SCHEMBL28812676 | 0.89 | CTNNB1 (0.47) | CTNNB1WNT3ASMN1; SMN2MAOBMAOA | |
| Benzofuran SCHEMBL7085367 | 0.84 | CTNNB1 (0.41) | CTNNB1WNT3AMAOBMAOAFTO | |
| Benzofuran SCHEMBL28870582 | 0.84 | CTNNB1 (0.45) | CTNNB1WNT3AALDH1A1SMN1; SMN2MAOB | |
| Benzofuran SCHEMBL28385283 | 0.83 | CTNNB1 (0.43) | CTNNB1WNT3AMAOBMAOALMNA | |
| Benzofuran SCHEMBL31275524 | 0.82 | CTNNB1 (0.47) | CTNNB1WNT3ANPC1ALDH1A1RAB9A | |
| Benzofuran SCHEMBL11368578 | 0.82 | CTNNB1 (0.47) | CTNNB1WNT3ANPC1ALDH1A1RAB9A | |
| Benzofuran SCHEMBL7029052 | 0.82 | CTNNB1 (0.47) | CTNNB1WNT3ANPC1ALDH1A1RAB9A | |
| Benzofuran SCHEMBL11121745 | 0.82 | CTNNB1 (0.50) | CTNNB1WNT3ANPC1RAB9AMAOB | |
| Benzofuran SCHEMBL5860505 | 0.82 | MAOA (0.39) | CTNNB1WNT3AMAOBMAOAFTO | |
| Benzofuran SCHEMBL11121861 | 0.82 | CTNNB1 (0.50) | CTNNB1WNT3ANPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108658908-B | 1,3- bis- replaces ketene compounds and its application | 广州必贝特医药技术有限公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-108658908-A | 1,3- bis- substitution ketene compounds and its application | 广州必贝特医药技术有限公司 | 2018-10-16 | — | — | CN | disclosed |