Benzofuran

Benzofuran

SCHEMBL28385283

CCCCC(=O)CCCC.c1ccc2occc2c1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 5/20 0.43
WNT3A P56704 5/20 0.43
FAAH O00519 6/20 0.43
IAPP P10997 2/20 0.41
MAOB P27338 2/20 0.41
CES1 P23141 2/20 0.40
CES2 O00748 1/20 0.40
LMNA P02545 2/20 0.40
HTT P42858 1/20 0.40
MAOA P21397 1/20 0.39
HDAC3 O15379 1/20 0.39
ELANE P08246 1/20 0.38
DAGLA Q9Y4D2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzofuran SCHEMBL29006510 0.84 MEN1 (0.39) CTNNB1WNT3AMAOBLMNAHTT
Benzofuran SCHEMBL28244692 0.83 CTNNB1 (0.44) CTNNB1WNT3AMAOBLMNAMAOA
Benzofuran SCHEMBL5860505 0.80 MAOA (0.39) CTNNB1WNT3AMAOBLMNAMAOA
Benzofuran SCHEMBL28812676 0.80 CTNNB1 (0.47) CTNNB1WNT3AMAOBCES1CES2
Benzofuran SCHEMBL28870582 0.79 CTNNB1 (0.45) CTNNB1WNT3AMAOBLMNAMAOA
Benzofuran SCHEMBL7085367 0.79 CTNNB1 (0.41) CTNNB1WNT3AMAOBMAOA
Benzofuran SCHEMBL31275524 0.77 CTNNB1 (0.47) CTNNB1WNT3AMAOBLMNAMAOA
Benzofuran SCHEMBL7029052 0.77 CTNNB1 (0.47) CTNNB1WNT3AMAOBLMNAMAOA
Benzofuran SCHEMBL11368578 0.77 CTNNB1 (0.47) CTNNB1WNT3AMAOBLMNAMAOA
Benzofuran SCHEMBL28762550 0.77 FAAH (0.37) CTNNB1WNT3AFAAHMAOBCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110938196-A Low-melting-point polyester and preparation method thereof 中国纺织科学研究院有限公司 2020-03-31 CN claimed
CN-110938196-A Low-melting-point polyester and preparation method thereof 中国纺织科学研究院有限公司 2020-03-31 CN disclosed