Benzylacetone

Benzylacetone

SCHEMBL28244875

CC(=O)CCc1ccccc1.c1ccc2[nH]ccc2c1

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.64
TRPA1 O75762 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
ITGB2 P05107 1/20 0.52
ICAM1 P05362 1/20 0.52
ITGAL P20701 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
AHR P35869 1/20 0.52
ADK P55263 1/20 0.52
CTNNB1 P35222 1/20 0.44
WNT3A P56704 1/20 0.44
KEAP1 Q14145 1/20 0.44
SLC6A2 P23975 3/20 0.42
SLC6A4 P31645 3/20 0.42
SLC6A3 Q01959 3/20 0.42
FFAR1 O14842 1/20 0.42
MAPK14 Q16539 3/20 0.41
HDAC2 Q92769 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl Propionic Acid SCHEMBL27592230 0.88 KEAP1 (0.61) ALDH1A1TRPA1CA1CA2ITGB2
Indole SCHEMBL8692212 0.82 TRPA1 (0.71) ALDH1A1TRPA1CA1CA2ITGB2
Indole SCHEMBL15552 0.82 TRPA1 (0.71) ALDH1A1TRPA1CA1CA2ITGB2
Indole SCHEMBL28064106 0.82 TRPA1 (0.71) ALDH1A1TRPA1CA1CA2ITGB2
Indole SCHEMBL14576777 0.80 TRPA1 (0.68) ALDH1A1TRPA1CA1CA2ITGB2
Indole SCHEMBL14576595 0.80 TRPA1 (0.68) ALDH1A1TRPA1CA1CA2ITGB2
Indole SCHEMBL14576309 0.80 TRPA1 (0.68) ALDH1A1TRPA1CA1CA2ITGB2
Naphthalene SCHEMBL29066893 0.80 TRPA1 (0.68) ALDH1A1TRPA1CA1CA2ITGB2
Indole SCHEMBL14576591 0.80 TRPA1 (0.68) ALDH1A1TRPA1CA1CA2ITGB2
Indole SCHEMBL14576774 0.80 TRPA1 (0.68) ALDH1A1TRPA1CA1CA2ITGB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108558794-A A kind of preparation method for reacting synthesis light-sensitive compound according to Claisen-Schmidt 北京化工大学 2018-09-21 CN disclosed