Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.79 |
| ▸ | EYA3 | Q99504 | 4/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245008 | 0.90 | CYP2C19 (0.79) | CYP2C19EYA3CYP2C9MAPTNPC1 | |
| SCHEMBL8994710 | 0.89 | CYP2C19 (1.00) | CYP2C19EYA3CYP2C9KDM7ASLC22A12 | |
| SCHEMBL28245013 | 0.87 | CYP2C19 (0.75) | CYP2C19EYA3CYP2C9MAPTSMN1; SMN2 | |
| SCHEMBL8994709 | 0.84 | CYP2C19 (1.00) | CYP2C19EYA3CYP2C9MAPTSMN1; SMN2 | |
| SCHEMBL28245011 | 0.84 | CYP2C19 (0.71) | CYP2C19EYA3CYP2C9MAPTKDM7A | |
| SCHEMBL11846277 | 0.84 | CYP2C19 (0.70) | CYP2C19EYA3CYP2C9MAPTSMN1; SMN2 | |
| SCHEMBL14552008 | 0.83 | HTT (0.62) | CYP2C19EYA3CYP2C9MAPTSMN1; SMN2 | |
| SCHEMBL28244402 | 0.82 | HTT (0.70) | CYP2C19EYA3CYP2C9MAPTNPC1 | |
| SCHEMBL12286119 | 0.81 | EYA3 (0.79) | CYP2C19EYA3CYP2C9MAPTSMN1; SMN2 | |
| SCHEMBL9316490 | 0.81 | CYP2C19 (0.73) | CYP2C19EYA3CYP2C9MAPTKDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484546-B | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-108484546-A | A kind of preparation method of 2- methyl -3- benzoyl benzofuran derivatives | 江南大学 | 2018-09-04 | — | — | CN | disclosed |