Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 6/20 | 0.73 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.69 |
| ▸ | EYA3 | Q99504 | 4/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444770 | 0.89 | CYP2C19 (0.65) | CYP2C19KDM7AEYA3CYP2C9THRA | |
| SCHEMBL9444836 | 0.87 | CYP2C19 (0.70) | CYP2C19KDM7AEYA3CYP2C9THRA | |
| SCHEMBL8994709 | 0.85 | CYP2C19 (1.00) | CYP2C19KDM7AEYA3CYP2C9MAPT | |
| SCHEMBL15426109 | 0.83 | KDM7A (0.67) | CYP2C19KDM7AEYA3CYP2C9RXFP1 | |
| SCHEMBL28245012 | 0.81 | CYP2C19 (0.79) | CYP2C19KDM7AEYA3CYP2C9THRA | |
| SCHEMBL28245008 | 0.81 | CYP2C19 (0.79) | CYP2C19KDM7AEYA3CYP2C9THRA | |
| SCHEMBL10598815 | 0.80 | EYA3 (0.54) | CYP2C19KDM7AEYA3CYP2C9RXFP1 | |
| SCHEMBL8994710 | 0.80 | CYP2C19 (1.00) | CYP2C19KDM7AEYA3CYP2C9THRA | |
| SCHEMBL28245013 | 0.79 | CYP2C19 (0.75) | CYP2C19KDM7AEYA3CYP2C9THRA | |
| SCHEMBL11845076 | 0.78 | CYP2C9 (0.60) | CYP2C19KDM7AEYA3CYP2C9RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584186-A1 | RECEPTOR LIGANDS. | KAROBIO AB (SE) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992020331-A1 | RECEPTOR LIGANDS | KAROBIO AKTIEBOLAG (SE) | 1992-11-26 | — | — | WO | disclosed |