SCHEMBL28246281

SCHEMBL28246281

Cc1cccc2c1c(C)c(C)n2C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 2/20 0.34
DAO P14920 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CTSG P08311 1/20 0.34
CMA1 P23946 1/20 0.34
MCL1 Q07820 2/20 0.33
LMNA P02545 2/20 0.33
CNR2 P34972 2/20 0.33
HTT P42858 1/20 0.33
PKM P14618 1/20 0.33
IDO1 P14902 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4096931 0.84 SLC9A1 (0.36) ALDH1A1HSD17B10TDP1MAPTDAO
SCHEMBL11606001 0.75 PTGDR2 (0.49) ALDH1A1KDM4EHTTMAPK1AKR1B1
SCHEMBL31668450 0.74 ALDH1A1 (0.54) ALDH1A1KDM4EHSD17B10TDP1MEN1
SCHEMBL27504693 0.74 ALDH1A1 (0.54) ALDH1A1KDM4EHSD17B10TDP1MEN1
SCHEMBL25534623 0.71 MAPT (0.44) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL29418964 0.71 MAPT (0.44) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL17700032 0.70 MEN1 (0.32) MEN1KMT2A
SCHEMBL17700014 0.70 AKR1B1 (0.34) DAOAKR1B1
Iodide SCHEMBL6250148 0.69 MAPT (0.43) ALDH1A1KDM4EHPGDHSD17B10TDP1
SCHEMBL2057102 0.69 DAO (0.34) ALDH1A1KDM4ETDP1MAPTDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108602770-A Novel biphenol compound or its salt 大鹏药品工业株式会社 2018-09-28 CN disclosed