Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314602 | 0.88 | KDM4E (0.51) | KDM4ERAB9AALDH1A1ERN1TUBB1 | |
| SCHEMBL28246323 | 0.87 | ALDH1A1 (0.67) | KDM4EALDH1A1ERN1TRIM24TYR | |
| SCHEMBL20488634 | 0.83 | KDM4E (0.59) | KDM4ERAB9AALDH1A1ERN1TUBB1 | |
| SCHEMBL27500190 | 0.82 | KDM4E (0.58) | KDM4ERAB9AALDH1A1ERN1TUBB1 | |
| SCHEMBL28676135 | 0.82 | ALDH1A1 (0.54) | KDM4ERAB9AALDH1A1ERN1TUBB1 | |
| SCHEMBL3221472 | 0.82 | BACE1 (0.58) | KDM4ERAB9AALDH1A1ERN1TUBB1 | |
| SCHEMBL172939 | 0.81 | ALDH1A1 (0.71) | KDM4EALDH1A1ERN1TUBB1TRIM24 | |
| SCHEMBL29392394 | 0.81 | ALDH1A1 (0.71) | KDM4EALDH1A1ERN1TUBB1TRIM24 | |
| SCHEMBL1808738 | 0.81 | KDM4E (0.53) | KDM4ERAB9AALDH1A1ERN1TUBB1 | |
| SCHEMBL9155251 | 0.81 | KDM4E (0.56) | KDM4ERAB9AALDH1A1ERN1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108570030-A | A kind of preparation method of the double chromone derivatives of natural products | 西北大学 | 2018-09-25 | — | — | CN | disclosed |