Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049103 | 0.89 | RAB9A (0.62) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL28245733 | 0.86 | GAA (0.46) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL28245757 | 0.86 | RAB9A (0.56) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049072 | 0.85 | TRPM8 (0.64) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL2069278 | 0.77 | RAB9A (1.00) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049277 | 0.76 | GAA (0.58) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL5196156 | 0.76 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049166 | 0.75 | TRPM8 (0.62) | RAB9AKDM4EGAAMAPTMEN1 | |
| SCHEMBL27997095 | 0.74 | GAA (0.43) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049178 | 0.74 | TRPM8 (0.61) | RAB9ASMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220069-B | Trpm8 antagonists | 多姆皮制药公司 | 2018-10-02 | — | — | CN | claimed |