Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997095 | 0.88 | GAA (0.43) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049277 | 0.87 | GAA (0.58) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL28246572 | 0.86 | RAB9A (0.61) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049292 | 0.83 | TRPM8 (0.64) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049469 | 0.78 | TRPM8 (0.50) | SMN1; SMN2KDM4EMAPTALDH1A1TRPM8 | |
| SCHEMBL28245733 | 0.78 | GAA (0.46) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL5196156 | 0.77 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL28816333 | 0.74 | RAB9A (0.56) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL15049103 | 0.74 | RAB9A (0.62) | RAB9ASMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL874365 | 0.74 | GAA (0.47) | RAB9ASMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220069-B | Trpm8 antagonists | 多姆皮制药公司 | 2018-10-02 | — | — | CN | claimed |