SCHEMBL28246731

SCHEMBL28246731

FC1CC=Cc2c1ccc1ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
HSD17B10 Q99714 4/20 0.37
CYP2A6 P11509 3/20 0.37
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
KDM1A O60341 1/20 0.36
HPRT1 P00492 1/20 0.34
MTNR1A P48039 1/20 0.34
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 3/20 0.32
HPGD P15428 2/20 0.32
HIF1A Q16665 1/20 0.32
CYP1B1 Q16678 1/20 0.32
THRB P10828 1/20 0.32
LMNA P02545 1/20 0.32
DRD2 P14416 1/20 0.32
SLC6A4 P31645 1/20 0.32
POLB P06746 1/20 0.32
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4960740 0.83 ALDH1A1 (0.37) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL29560738 0.79 ALDH1A1 (0.37) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL21283608 0.79 KDM1A (0.43) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL10783887 0.79 KDM4E (0.38) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL10457842 0.79 ALDH1A1 (0.37) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL9302630 0.79 ALDH1A1 (0.37) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL29913613 0.77 LMNA (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL2576862 0.76 ALDH1A1 (0.38) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL11221810 0.76 CA1 (0.33) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL9682849 0.74 CYP1A2 (0.39) ALDH1A1HSD17B10TDP1MTNR1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108587646-A A kind of liquid-crystal compounds containing four fluoro dihydro phenanthrene structures and its application 烟台丰蓬液晶材料有限公司 2018-09-28 CN claimed
CN-108587646-A A kind of liquid-crystal compounds containing four fluoro dihydro phenanthrene structures and its application 烟台丰蓬液晶材料有限公司 2018-09-28 CN disclosed
CN-108587646-A A kind of liquid-crystal compounds containing four fluoro dihydro phenanthrene structures and its application 烟台丰蓬液晶材料有限公司 2018-09-28 CN disclosed