Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457842 | 0.78 | ALDH1A1 (0.37) | CYP1A2HIF1ANR4A1NR4A2NR4A3 | |
| SCHEMBL29560738 | 0.78 | ALDH1A1 (0.37) | CYP1A2HIF1ANR4A1NR4A2NR4A3 | |
| SCHEMBL29913613 | 0.75 | LMNA (0.46) | MTNR1AKDM4ETDP1ALDH1A1HSD17B10 | |
| SCHEMBL10783887 | 0.74 | KDM4E (0.38) | CYP1A2MTNR1AKDM4EGAATDP1 | |
| SCHEMBL9302630 | 0.74 | ALDH1A1 (0.37) | CYP1A2CYP2C9CYP2C19HIF1AMTNR1A | |
| SCHEMBL21283608 | 0.74 | KDM1A (0.43) | HIF1AMTNR1AKDM4EGAATDP1 | |
| SCHEMBL4960740 | 0.74 | ALDH1A1 (0.37) | CYP1A2HIF1AMTNR1AKDM4ETDP1 | |
| SCHEMBL28246731 | 0.74 | ALDH1A1 (0.37) | CYP1A2HIF1AMTNR1AKDM4ETDP1 | |
| SCHEMBL2576862 | 0.74 | ALDH1A1 (0.38) | CYP1A2CYP2D6CYP2C9CYP2C19HIF1A | |
| SCHEMBL27657807 | 0.73 | MTNR1A (0.35) | MTNR1AMTNR1BKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141934-A | Nervous system disorders | WARNER-LAMBERT COMPANY (US) | 1992-08-25 | — | — | US | disclosed |