Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.35 |
| ▸ | PDE8A | O60658 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368919 | 0.75 | HCRTR2 (0.39) | — | |
| SCHEMBL30259181 | 0.75 | HCRTR2 (0.39) | — | |
| SCHEMBL20606958 | 0.72 | MBOAT4 (0.33) | MBOAT4PDE8A | |
| SCHEMBL2208595 | 0.72 | AURKA (0.43) | HPGDSMN1; SMN2 | |
| SCHEMBL18952506 | 0.72 | PDE8A (0.31) | MBOAT4PDE8A | |
| Methyl Alcohol SCHEMBL4441755 | 0.69 | AURKA (0.41) | HPGDSMN1; SMN2 | |
| SCHEMBL20607010 | 0.69 | MBOAT4 (0.34) | MBOAT4 | |
| SCHEMBL25254061 | 0.69 | MBOAT4 (0.32) | HPGDSMN1; SMN2MBOAT4PDE8A | |
| SCHEMBL29332333 | 0.68 | TAAR1 (0.42) | — | |
| SCHEMBL30977446 | 0.67 | MBOAT4 (0.39) | MBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699037-A | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | 加拉帕戈斯股份有限公司 | 2018-10-23 | — | — | CN | disclosed |