Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 4/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20606881 | 0.83 | MBOAT4 (0.41) | MBOAT4PRKD3MAPK8 | |
| SCHEMBL20606954 | 0.81 | MAPK8 (0.42) | PRKD3MAPK8 | |
| SCHEMBL20606958 | 0.78 | MBOAT4 (0.33) | MBOAT4 | |
| SCHEMBL20606763 | 0.72 | POLB (0.36) | MBOAT4 | |
| SCHEMBL28247334 | 0.69 | HPGD (0.39) | MBOAT4 | |
| SCHEMBL30977446 | 0.67 | MBOAT4 (0.39) | MBOAT4 | |
| SCHEMBL5780985 | 0.66 | LMNA (0.38) | MBOAT4 | |
| SCHEMBL29082185 | 0.65 | MBOAT4 (0.34) | MBOAT4 | |
| SCHEMBL20606929 | 0.64 | MAPK8 (0.46) | PRKD3MAPK8 | |
| SCHEMBL23909016 | 0.63 | MBOAT4 (0.36) | MBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423445-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2020-04-01 | — | — | EP | disclosed |
| EP-3423445-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | Galapagos NV (BE) | 2019-01-09 | — | — | EP | disclosed |