3-Methylpyridine

3-Methylpyridine

SCHEMBL28247355

C1COCCN1.Cc1cccnc1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 6/20 0.41
CHRNA4 P43681 6/20 0.41
CYP2A6 P11509 2/20 0.39
CYP3A4 P08684 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP2C9 P11712 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
CHRNA7 P36544 2/20 0.38
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 2/20 0.37
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CYP1A2 P05177 1/20 0.37
ALDH1A1 P00352 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
NISCH Q9Y2I1 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Methylpyridine SCHEMBL27313811 0.87 CHRNB2 (0.47) CHRNB2CHRNA4CYP2A6CYP3A4MEN1
3-Methylpyridine SCHEMBL826266 0.85 CYP2A6 (0.46) CHRNB2CHRNA4CYP2A6CYP3A4KDM4E
3-Methylpyridine SCHEMBL27858700 0.80
Morpholine SCHEMBL27741975 0.79 CHRNB2 (0.40) CHRNB2CHRNA4CYP2A6CYP3A4MEN1
3-Methylpyridine SCHEMBL820155 0.78 CYP2A6 (0.54) CHRNB2CHRNA4CYP2A6CYP3A4KDM4E
3-Methylpyridine SCHEMBL29361018 0.78
3-Methylpyridine SCHEMBL10530 0.78
Morpholine SCHEMBL6137775 0.77 MEN1 (0.44) CHRNB2CHRNA4CYP3A4MEN1KMT2A
Toluene SCHEMBL3946837 0.77 LMNA (0.50) MEN1KMT2ACYP2C9KDM4EGAA
3-Methylpyridine SCHEMBL6514889 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109956942-A Tryptamines ketones derivant and application thereof 上海翔锦生物科技有限公司 2019-07-02 CN disclosed
CN-104693193-B Aryl methoxy isoindoline derivative and composition and their application method including it 细胞基因公司 2018-09-18 CN disclosed