Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL8675145 | 0.93 | DRD1 (0.61) | LMNAHSD17B10DRD1CA12CA1 | |
| Isophthalic Acid SCHEMBL8664124 | 0.90 | CA12 (0.52) | LMNAHSD17B10DRD1CA12CA1 | |
| SCHEMBL27344332 | 0.87 | LMNA (0.50) | LMNAHSD17B10MAPTDAOTSHR | |
| SCHEMBL938192 | 0.85 | ALDH1A1 (0.56) | DRD1CA12CA1CA2CA3 | |
| SCHEMBL361277 | 0.85 | LMNA (0.58) | LMNAHSD17B10DRD1ESR1TDP1 | |
| Bicarbonate SCHEMBL10591562 | 0.85 | ESR1 (0.58) | LMNAHSD17B10DRD1ESR1TDP1 | |
| Benzene SCHEMBL28219933 | 0.84 | ESR1 (0.62) | LMNAHSD17B10DRD1ESR1TDP1 | |
| SCHEMBL74326 | 0.82 | ESR1 (0.65) | LMNAHSD17B10DRD1ESR1TDP1 | |
| SCHEMBL1171043 | 0.82 | ESR1 (0.65) | LMNAHSD17B10DRD1ESR1TDP1 | |
| Hydroquinone SCHEMBL28097256 | 0.82 | ESR1 (0.65) | LMNAHSD17B10DRD1ESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608682-A | Manufacturing method, porous polyimide film and the partition for having used the porous polyimide film of porous polyimide film | 东京应化工业株式会社 | 2019-04-12 | — | — | CN | disclosed |
| CN-106133077-B | Composition for forming release layer | 日产化学工业株式会社 | 2018-11-06 | — | — | CN | disclosed |
| CN-108690494-A | Peeling layer formation composition | 日产化学工业株式会社 | 2018-10-23 | — | — | CN | disclosed |
| CN-108690495-A | Peeling layer formation composition | 日产化学工业株式会社 | 2018-10-23 | — | — | CN | disclosed |