Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28247779 | 0.93 | LMNA (0.54) | DRD1CA12CA1CA2CA7 | |
| SCHEMBL938192 | 0.92 | ALDH1A1 (0.56) | DRD1CA12CA1CA2CA7 | |
| Bicarbonate SCHEMBL10591562 | 0.88 | ESR1 (0.58) | DRD1LMNAMAPTESR1CYP1A2 | |
| SCHEMBL27344332 | 0.86 | LMNA (0.50) | LMNAMAPTSRD5A2HSD17B10ALDH1A1 | |
| Isophthalic Acid SCHEMBL8664124 | 0.86 | CA12 (0.52) | DRD1CA12CA1CA2CA7 | |
| SCHEMBL1171043 | 0.85 | ESR1 (0.65) | DRD1LMNAMAPTESR1CYP1A2 | |
| Hydroquinone SCHEMBL28097256 | 0.85 | ESR1 (0.65) | DRD1LMNAMAPTESR1CYP1A2 | |
| SCHEMBL74326 | 0.85 | ESR1 (0.65) | DRD1LMNAMAPTESR1CYP1A2 | |
| SCHEMBL31712136 | 0.84 | ESR1 (0.54) | DRD1LMNAMAPTESR1CYP1A2 | |
| SCHEMBL28544659 | 0.83 | ESR1 (0.62) | DRD1LMNAMAPTESR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795693-A | Carrier for electrophotography, two component-type developer and image forming method | CANON KABUSHIKI KAISHA (JP) | 1998-08-18 | — | — | US | disclosed |
| US-5143809-A | Polyesters from bisphenol type diol, dicarboxylic acid and tricarboxylic acid | KONICA CORPORATION (JP) | 1992-09-01 | — | — | US | disclosed |