Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.61 |
| ▸ | VNN1 | O95497 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248162 | 0.98 | HDAC6 (0.60) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28247582 | 0.95 | HDAC6 (0.60) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL1030969 | 0.81 | HDAC6 (0.64) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28248252 | 0.79 | HDAC6 (0.52) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28247580 | 0.79 | HDAC6 (0.49) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28247670 | 0.79 | HDAC6 (0.57) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL24968632 | 0.78 | HDAC6 (0.62) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28248171 | 0.78 | VNN1 (0.58) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL28248165 | 0.77 | HDAC6 (0.44) | HDAC6HDAC3HDAC1HDAC2VNN1 | |
| SCHEMBL4729765 | 0.77 | HDAC3 (1.00) | HDAC6HDAC3HDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699048-A | Oxadiazolamide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same | 株式会社钟根堂 | 2018-10-23 | — | — | CN | disclosed |