SCHEMBL28248348

SCHEMBL28248348

O=C(OCC(O)CO)C(F)(F)F.[NaH]

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
KDM4E B2RXH2 1/20 0.41
DUSP3 P51452 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PRKCA P17252 1/20 0.36
DGKA P23743 1/20 0.35
HTT P42858 1/20 0.34
FAAH O00519 2/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20225119 0.98 LMNA (0.42) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL24436724 0.82 LMNA (0.40) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL14700446 0.82 KDM4E (0.43) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL24229139 0.81 HTT (0.35) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL29442979 0.79 HTT (0.34) HTT
Trifluoroacetic Acid SCHEMBL29117404 0.79 LMNA (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL8440606 0.78 LMNA (0.33) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL10225090 0.77 ALDH1A1 (0.42) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL26548897 0.77 KDM4E (0.40) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL136506 0.77 LMNA (0.42) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108752584-A A kind of corona-resistant polyimide based composites and preparation method thereof 中国科学院长春应用化学研究所 2018-11-06 CN disclosed
CN-108676163-A A kind of high-performance polyimide based composites and preparation method thereof 中国科学院长春应用化学研究所 2018-10-19 CN disclosed