Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20225119 | 0.79 | LMNA (0.42) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28248348 | 0.78 | LMNA (0.41) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL4801146 | 0.72 | LMNA (0.39) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL3380530 | 0.71 | LMNA (0.34) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL30755 | 0.69 | LMNA (0.53) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL8071078 | 0.69 | LMNA (0.37) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL29117404 | 0.69 | LMNA (0.41) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL4808325 | 0.69 | LMNA (0.44) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL28363636 | 0.69 | LMNA (0.37) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL7623085 | 0.68 | ALDH1A1 (0.39) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872135-A | ENZYME INHIBITORS | MERK & CO., INC. (US) | 1999-02-16 | — | — | US | disclosed |
| WO-1996010035-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |