SCHEMBL28248403

SCHEMBL28248403

CC(C)(C)Oc1ccc(Pc2ccc(OC(C)(C)C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
KIF11 P52732 1/20 0.36
ACACB O00763 2/20 0.33
RIPK1 Q13546 1/20 0.33
PPARA Q07869 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C19 P33261 1/20 0.32
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2154296 0.98 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3MEN1KMT2A
Hydrochloric Acid SCHEMBL2154309 0.89 KIF11 (0.39) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL26746 0.84 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL11451453 0.81 MEN1 (0.38) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL57369 0.77 MEN1 (0.57) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL198046 0.76 RIPK1 (0.43) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL19339945 0.76 MAPT (0.44) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL18866585 0.76 MAPT (0.44) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL7270832 0.75 SLC6A2 (0.37) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL5285766 0.74 CA1 (0.61) MEN1KMT2AKDM4ECYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106083927-B Phosphino- amidine compound, metal complex, antigravity system and their oligomeric or olefin polymerization purposes 切弗朗菲利浦化学公司 2018-10-26 CN disclosed