Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814085 | 0.87 | TSHR (0.50) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL27978188 | 0.84 | MAPT (0.51) | HSD17B10TSHRCYP3A4TP53HPGD | |
| SCHEMBL27930468 | 0.76 | TSHR (0.55) | ALOX15HSD17B10L3MBTL1TSHRCYP3A4 | |
| SCHEMBL1896801 | 0.74 | TDP1 (0.56) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL3280548 | 0.72 | GPR35 (0.54) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL5881005 | 0.72 | TSHR (0.44) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL21811800 | 0.71 | TSHR (0.53) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL258792 | 0.71 | GPR35 (0.55) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL28240513 | 0.71 | GPR35 (0.52) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL535242 | 0.70 | ALOX15 (0.74) | ALOX15MAPK1HSD17B10L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883198-A | ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | 卫材研究发展管理有限公司 | 2018-11-23 | — | — | CN | disclosed |