Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.78 |
| ▸ | ARG2 | P78540 | 4/20 | 0.52 |
| ▸ | ARG1 | P05089 | 3/20 | 0.52 |
| ▸ | NOS2 | P35228 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornithine SCHEMBL30695803 | 0.95 | — | — | |
| Ornithine SCHEMBL30563013 | 0.95 | — | — | |
| Ornithine SCHEMBL20362354 | 0.95 | — | — | |
| Ornithine Aketoglutarate SCHEMBL1326163 | 0.95 | GSR (0.86) | GSRARG2ARG1NOS2CYP1A2 | |
| D-Ornithine SCHEMBL43724 | 0.95 | — | — | |
| Ornithine SCHEMBL30695804 | 0.95 | — | — | |
| Ornithine Aketoglutarate SCHEMBL42530 | 0.95 | GSR (0.86) | GSRARG2ARG1NOS2CYP1A2 | |
| Ornithine Aketoglutarate SCHEMBL8578 | 0.95 | — | — | |
| Ornithine SCHEMBL624782 | 0.95 | GSR (0.86) | GSRARG2ARG1NOS2CYP1A2 | |
| D-Ornithine SCHEMBL1537220 | 0.95 | GSR (0.86) | GSRARG2ARG1NOS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579465-B | Variant AAV and compositions, methods and uses for gene transfer into cells, organs and tissues | 费城儿童医院 | 2019-09-10 | — | — | CN | disclosed |
| CN-108603174-A | Expandable method for producing recombinant adeno-associated virus (AAV) vectors in serum-free suspension cell culture system suitable for clinical application | 星火治疗有限公司 | 2018-09-28 | — | — | CN | disclosed |