Benzoic Acid 2-Methylpropyl Ester

Benzoic Acid 2-Methylpropyl Ester

SCHEMBL28249378

CC(C)COC(=O)C(C)C.CC(C)COC(=O)c1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
TSHR P16473 2/20 0.61
ADRB2 P07550 2/20 0.56
ADRB1 P08588 2/20 0.56
ADRB3 P13945 2/20 0.56
PLA2G1B P04054 1/20 0.55
ATG4B Q9Y4P1 1/20 0.55
LMNA P02545 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49
HIF1A Q16665 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KMT2A Q03164 1/20 0.49
RAB9A P51151 1/20 0.47
SLC1A5 Q15758 1/20 0.46
ELANE P08246 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid 2-Methylpropyl Ester SCHEMBL298176 0.93 TSHR (0.69) ALDH1A1TSHRADRB2ADRB1ADRB3
Benzoic Acid 2-Methylpropyl Ester SCHEMBL20530394 0.93 TSHR (0.69) ALDH1A1TSHRADRB2ADRB1ADRB3
Benzoic Acid 2-Methylpropyl Ester SCHEMBL27827529 0.91 TSHR (0.67) ALDH1A1TSHRADRB2ADRB1ADRB3
Benzoic Acid 2-Methylpropyl Ester SCHEMBL28242226 0.91 TSHR (0.67) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL22667354 0.88 ADRB2 (0.68) ALDH1A1ADRB2ADRB1ADRB3LMNA
Benzoic Acid 2-Methylpropyl Ester SCHEMBL31190186 0.86 ALDH1A1 (0.61) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL11349165 0.86 ALDH1A1 (0.61) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL110051 0.83 ALDH1A1 (0.64) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL24325565 0.82 LMNA (0.65) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL17928312 0.82 LMNA (0.55) ALDH1A1TSHRADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108601958-A Pro-perfume compositions 爱客多有限公司 2018-09-28 CN disclosed