Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AANAT | Q16613 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.65 |
| ▸ | CTSC | P53634 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768952 | 0.86 | AANAT (0.65) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL1768953 | 0.86 | AANAT (0.65) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL10575207 | 0.86 | MEN1 (0.68) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL13560942 | 0.86 | MEN1 (0.66) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL15176753 | 0.85 | AANAT (0.64) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL15145390 | 0.83 | CTSC (0.71) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL761706 | 0.83 | MEN1 (0.75) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL6703004 | 0.83 | AANAT (0.75) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL761155 | 0.83 | MTNR1A (0.76) | AANATMEN1KMT2ATSHRLMNA | |
| SCHEMBL31114206 | 0.83 | MTNR1A (0.76) | AANATMEN1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020179-B9 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHESTVO OTECHESTVENNYE LEKARSTVA (RU) | 2011-02-02 | — | — | EP | disclosed |
| EP-2229935-A1 | Peptide derivatives or pharmaceutically acceptable salts thereof, method for producing the same, use of said derivatives and pharmaceutical composition | Nebolsin, Vladimir Evgenievich (RU) | 2010-09-22 | — | — | EP | disclosed |
| EP-1020179-B1 | PEPTIDE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PRODUCING THE SAME, USE OF SAID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | OTKRYTOE AKTSIONERNOE OBSCHEST (RU) | 2009-12-09 | — | — | EP | disclosed |