Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | SPR | P35270 | 1/20 | 0.70 |
| ▸ | MMP9 | P14780 | 1/20 | 0.67 |
| ▸ | AANAT | Q16613 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17037428 | 0.91 | MEN1 (0.70) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL18595162 | 0.89 | MEN1 (0.76) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL7677879 | 0.88 | MEN1 (0.67) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL9118606 | 0.88 | MEN1 (0.71) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL6365945 | 0.86 | MEN1 (0.65) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL15145390 | 0.86 | CTSC (0.71) | MEN1KMT2ATSHRALDH1A1MAPT | |
| Nb-Acetyltryptamine SCHEMBL468850 | 0.85 | MEN1 (1.00) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL10554058 | 0.85 | MEN1 (0.64) | MEN1KMT2ATSHRALDH1A1MAPT | |
| SCHEMBL7612467 | 0.85 | MEN1 (0.64) | MEN1KMT2ATSHRALDH1A1MAPT | |
| Nb-Acetyltryptamine SCHEMBL29669230 | 0.84 | MEN1 (0.97) | MEN1KMT2ATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218374-A1 | Nucleic Acid Compounds That Bind Coronavirus Proteins | SOMALOGIC OPERATING CO., INC. (US) | 2024-07-04 | — | — | US | disclosed |
| US-20240218374-A1 | Nucleic Acid Compounds That Bind Coronavirus Proteins | SOMALOGIC OPERATING CO., INC. (US) | 2024-07-04 | — | — | US | disclosed |
| US-20230193287-A1 | Nucleic Acid Compounds for Binding Growth Differentiation Factor 11 | SOMALOGIC OPERATING CO., INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230024434-A1 | Methods for Developing Personalized Drug Treatment Plans and Targeted Drug Development Based on Proteomic Profiles | SOMALOGIC, INC. (US) | 2023-01-26 | — | — | US | disclosed |
| US-11111495-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-10889556-B2 | Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-01-12 | — | — | US | disclosed |
| US-20190330634-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC OPERATING CO., INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190106398-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-04-11 | — | — | US | disclosed |
| US-20180187197-A1 | Multiaptamer Target Detection | SOMALOGIC OPERATING CO., INC. | 2018-07-05 | — | — | US | disclosed |
| US-9994857-B2 | PDGF and VEGF aptamers having improved stability and their use in treating PDGF and VEGF mediated diseases and disorders | SOMALOGIC, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| US-7947447-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947447-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-20110082286-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-20110082286-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| WO-2011006075-A1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| US-7855054-B2 | Multiplexed analyses of test samples | SOMALOGIC, INC. (US) | 2010-12-21 | — | — | US | disclosed |
| US-7855054-B2 | Multiplexed analyses of test samples | SOMALOGIC, INC. (US) | 2010-12-21 | — | — | US | disclosed |
| US-20100105683-A1 | COMPOUNDS USEFUL FOR INHIBITING CHK1 | KEEGAN KATHLEEN S | 2010-04-29 | — | — | US | disclosed |
| US-7608618-B2 | Urea or thiourea substituted 1,4-pyrazine compounds useful as anti-cancer agents and for inhibiting Chk1 | ICOS CORPORATION (US) | 2009-10-27 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190106398-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | POLRMT, RNASE1, POLM | MEN1 3312/4885KMT2A 1216/4885TSHR 3661/4885 |
| US-20230193287-A1 | Nucleic Acid Compounds for Binding Growth Differentiation Factor 11 | MSTN, S100A11, IGF2BP1 | MEN1 1586/4885KMT2A 3322/4885TSHR 512/4885 |
| US-20100105683-A1 | COMPOUNDS USEFUL FOR INHIBITING CHK1 | CHEK1, PCNA, CHEK2 | MEN1 1983/4885KMT2A 1546/4885TSHR 4083/4885 |
| US-20110082286-A1 | Method for Generating Aptamers with Improved Off-Rates | DDX1, DDX3X, DDX18 | MEN1 4259/4885KMT2A 1608/4885TSHR 817/4885 |
| US-20240218374-A1 | Nucleic Acid Compounds That Bind Coronavirus Proteins | SARS1, RNGTT, PABPC1 | MEN1 4651/4885KMT2A 3666/4885TSHR 3407/4885 |
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | MEN1 234/4885KMT2A 3668/4885TSHR 50/4885 |
| US-10889556-B2 | Compositions and methods for inhibiting influenza RNA polymerase PA endonuclease | POLRMT, RNASE1, POLM | MEN1 3312/4885KMT2A 1216/4885TSHR 3661/4885 |
| US-20230024434-A1 | Methods for Developing Personalized Drug Treatment Plans and Targeted Drug Development Based on Proteomic Profiles | TTR, TPX2, FABP1 | MEN1 4410/4885KMT2A 3305/4885TSHR 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.