Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28220687 | 0.78 | PSMD14 (0.52) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL29091357 | 0.77 | PARP1 (0.50) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL9876503 | 0.77 | PSMD14 (0.55) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL17541536 | 0.74 | PSMD14 (0.52) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL28037486 | 0.74 | PSMD14 (0.52) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL8686129 | 0.73 | PARP1 (0.49) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL16084043 | 0.73 | MMP2 (0.55) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL1063947 | 0.73 | PARP1 (0.46) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL5185814 | 0.72 | PARP1 (0.47) | PARP1METAP2METAP1MMP2TSHR | |
| SCHEMBL28117700 | 0.72 | MAPT (0.49) | PARP1METAP2METAP1MMP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108904801-A | A kind of multifunctional nano vesica and preparation method thereof | 中山大学 | 2018-11-30 | — | — | CN | disclosed |