Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MYOC | Q99972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299508 | 0.89 | GAA (0.57) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL9237410 | 0.79 | GAA (0.57) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL4752026 | 0.76 | GAA (0.58) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL14307582 | 0.76 | GAA (0.58) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL8211917 | 0.75 | KMT2A (0.47) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL4683792 | 0.74 | GAA (0.60) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL27368803 | 0.74 | GAA (0.59) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL10712258 | 0.74 | BCL9 (0.53) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL2191784 | 0.72 | GAA (0.61) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL22364390 | 0.72 | GAA (0.61) | GAABCL9CTNNB1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699063-A | Synthesis process of luccotinib | 正大天晴药业集团股份有限公司 | 2018-10-23 | — | — | CN | disclosed |