Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | BCL9 | O00512 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MYOC | Q99972 | 1/20 | 0.50 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063519 | 0.83 | GAA (0.65) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL26374 | 0.83 | GAA (0.65) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL2748042 | 0.82 | GAA (0.62) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL26375 | 0.82 | GAA (0.62) | GAABCL9CTNNB1KMT2APKM | |
| Hydrochloric Acid SCHEMBL7895043 | 0.82 | GAA (0.62) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL23084891 | 0.82 | GAA (0.62) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL3125295 | 0.82 | GAA (0.62) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL20377184 | 0.81 | SMN1; SMN2 (0.64) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL6322393 | 0.81 | SMN1; SMN2 (0.64) | GAABCL9CTNNB1KMT2APKM | |
| SCHEMBL8741192 | 0.81 | ALDH1A1 (0.60) | GAABCL9CTNNB1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351738-A1 | PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO)PIPERIDIN-3-OL | Sumitomo Chemical Company, Limited (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-20110172431-A1 | PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO) PIPERIDIN-3-OL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-07-14 | — | — | US | disclosed |
| US-7906629-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-03-15 | — | — | US | disclosed |
| US-7649085-B2 | Saquinavir conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| EP-1809672-B1 | ATAZANAVIR CONJUGATES AND ANTIBIBODIES USEFUL IN IMMUNOSSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2009-09-09 | — | — | EP | disclosed |
| US-7569678-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-7482437-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1888581-A2 | HIV-INTEGRASE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2008-02-20 | — | — | EP | disclosed |
| US-20080021201-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SIGLER GERALD F | 2008-01-24 | — | — | US | disclosed |
| US-20070155959-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SIGLER GERALD F | 2007-07-05 | — | — | US | disclosed |
| US-20040127689-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2004-07-01 | — | — | US | disclosed |
| EP-1409546-A2 | PROTEASE INHIBITOR CONJUGATES AND ANTIBODIES USEFUL IN IMMUNOASSAY | Roche Diagnostics GmbH (DE) | 2004-04-21 | — | — | EP | disclosed |
| US-20030100088-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003006506-A2 | PROTEASE INHIBITOR CONJUGATES AND ANTIBODIES USEFUL IN IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2003-01-23 | — | — | WO | disclosed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5075208-A | Releasing a photographically useful compound upon reduction | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-4994363-A | Silver halide light-sensitive material containing a compound releasing a photographically useful group | FUJI PHOTO FILM CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| US-4840887-A | USEFUL GROUP RELEASED BY CLEAVAGE BETWEEN SULFONYL GROUP AND A NITROGEN, SULFUR OR OXYGEN ATOM; STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1989-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100088-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, SPR | GAA 287/4885BCL9 2708/4885CTNNB1 4070/4885 |
| US-20040127689-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, DNPEP | GAA 207/4885BCL9 2771/4885CTNNB1 4159/4885 |
| US-20080021201-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, SPR | GAA 394/4885BCL9 2354/4885CTNNB1 4221/4885 |
| US-20070155959-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, SPR | GAA 394/4885BCL9 2353/4885CTNNB1 4240/4885 |
| US-20110172431-A1 | PROCESS FOR PRODUCING 1-SUBSTITUTED TRANS-4-(SUBSTITUTED AMINO) PIPERIDIN-3-OL | TEAD4, TEAD3, TEAD2 | GAA 2624/4885BCL9 1430/4885CTNNB1 1534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.