Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299508 | 0.83 | GAA (0.57) | BCL9CTNNB1GAAHTR2AKMT2A | |
| SCHEMBL9237410 | 0.83 | GAA (0.57) | BCL9CTNNB1GAAHTR2AKMT2A | |
| SCHEMBL28323255 | 0.83 | BCL9 (0.51) | BCL9CTNNB1GAAHTR2AKMT2A | |
| SCHEMBL4854441 | 0.81 | MGLL (0.58) | BCL9CTNNB1GAAHTR2AKMT2A | |
| SCHEMBL4752026 | 0.80 | GAA (0.58) | BCL9CTNNB1GAAHTR2AKMT2A | |
| SCHEMBL14307582 | 0.80 | GAA (0.58) | BCL9CTNNB1GAAHTR2AKMT2A | |
| SCHEMBL11658704 | 0.79 | IDO1 (0.51) | HTR2AALDH1A1RAB9A | |
| Glycerin SCHEMBL5983875 | 0.79 | BCL9 (0.51) | BCL9CTNNB1GAAHTR2AKMT2A | |
| SCHEMBL5983878 | 0.79 | HTR2A (0.54) | BCL9CTNNB1GAAHTR2AKMT2A | |
| Bromide SCHEMBL11665376 | 0.79 | MEN1 (0.60) | GAAKMT2APKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4640835-A | PHYSIOLOGICALLY STABLE ANTICOAGULANTS | NIPPON CHEMIPHAR COMPANY, LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| US-4495285-A | Plasminogen activator derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-01-22 | — | — | US | disclosed |