Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251696 | 0.83 | LMNA (0.50) | LMNAALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL28251690 | 0.81 | LMNA (0.49) | LMNAALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL28251680 | 0.81 | LMNA (0.49) | LMNAALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL5355407 | 0.81 | LMNA (0.49) | LMNAALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL6660171 | 0.81 | CDK1 (0.63) | LMNAALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL31061395 | 0.80 | EGFR (0.59) | LMNAALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL4121599 | 0.78 | SRC (0.67) | LMNAALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL20041716 | 0.75 | YTHDC1 (0.66) | — | |
| SCHEMBL15518357 | 0.73 | NPC1 (0.46) | LMNAALDH1A1HTTTSHRMAPK1 | |
| SCHEMBL13196022 | 0.70 | NPC1 (0.45) | HTTMAPK1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108703970-A | Compound for activating AMPK and application thereof | 华安医学股份有限公司 | 2018-10-26 | — | — | CN | disclosed |