Malonic Acid

Malonic Acid

SCHEMBL28252452

O=C(O)CC(=O)O.OCCCC(CO)CO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.43
SRR Q9GZT4 1/20 0.43
CAMK2A Q9UQM7 1/20 0.40
PTPN1 P18031 1/20 0.38
FNTA P49354 1/20 0.38
FNTB P49356 1/20 0.38
GPR84 Q9NQS5 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
GSTK1 Q9Y2Q3 2/20 0.34
GRM8 O00222 1/20 0.30
GRM6 O15303 1/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GSR P00390 1/20 0.30
CYP1A2 P05177 1/20 0.30
GRIK1 P39086 1/20 0.30
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL11515132 0.88 CAMK2A (0.42) CAMK2APTPN1FNTAFNTBGPR84
Bicarbonate SCHEMBL1357296 0.87 CAMK2A (0.39) CAMK2APTPN1GPR84FFAR1FFAR4
Acetoacetic Acid SCHEMBL7708375 0.87 CAMK2A (0.34) LDHASRRCAMK2APTPN1FNTA
Succinic Acid SCHEMBL542104 0.86 CAMK2A (0.52) CAMK2APTPN1GPR84FFAR1FFAR4
Oxalic Acid SCHEMBL28437633 0.85 CAMK2A (0.38) CAMK2APTPN1FNTAFNTBGPR84
Thioglycolic Acid SCHEMBL27566083 0.84 GSTK1 (0.42) CAMK2APTPN1GPR84FFAR1FFAR4
Propionic Acid SCHEMBL20956275 0.84 FFAR3 (0.46) CAMK2APTPN1GPR84FFAR1FFAR4
Adipic Acid SCHEMBL7027047 0.84 FFAR1 (0.58) CAMK2APTPN1GPR84FFAR1FFAR4
Carbamic Acid SCHEMBL1073227 0.83 CAMK2A (0.36) CAMK2APTPN1GPR84FFAR1FFAR4
Acetic Acid SCHEMBL540581 0.83 ALDH1A1 (0.41) CAMK2APTPN1GPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884289-A (meth) acrylic resin composition, resin molded body, resin laminate, and method for producing (meth) acrylic resin composition 三菱化学株式会社 2018-11-23 CN disclosed