SCHEMBL28253236

SCHEMBL28253236

c1ccc(Oc2ccc(-c3cc[nH]c3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP19A1 P11511 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
LTA4H P09960 9/20 0.48
TSHR P16473 1/20 0.48
TNK2 Q07912 1/20 0.48
GSTP1 P09211 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SCN4A P35499 1/20 0.44
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
MAOA P21397 1/20 0.43
NISCH Q9Y2I1 1/20 0.42
TLR8 Q9NR97 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21277361 0.83 ALDH1A1 (0.47) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL28129946 0.81 LTA4H (0.55) LTA4HTSHRGSTP1NPC1RAB9A
SCHEMBL720957 0.80 ALDH1A1 (0.50) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL6406035 0.80 LTA4H (0.75) LTA4HTSHRGSTP1NPC1RAB9A
SCHEMBL197414 0.80 LTA4H (0.75) LTA4HTSHRGSTP1NPC1RAB9A
SCHEMBL2860844 0.80 LTA4H (0.75) LTA4HTSHRGSTP1NPC1RAB9A
SCHEMBL7759460 0.79 LTA4H (0.57) LTA4HTSHRGSTP1NPC1RAB9A
SCHEMBL28306614 0.78 ALDH1A1 (0.47) CYP1A2CYP3A4CYP2D6CYP19A1CYP2C9
SCHEMBL9190364 0.78 LTA4H (0.71) LTA4HTSHRGSTP1NPC1RAB9A
SCHEMBL21921128 0.78 LTA4H (0.71) LTA4HTSHRGSTP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108727230-A According to Shandong for Buddhist nun's intermediate and preparation method thereof 上海创诺医药集团有限公司 2018-11-02 CN claimed