SCHEMBL28253288

SCHEMBL28253288

Fc1ccc(-c2ccc(-c3ccccc3)[nH]2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 1/20 0.52
ERCC4 Q92889 1/20 0.52
GCGR P47871 1/20 0.49
MAPK14 Q16539 1/20 0.49
MAPT P10636 4/20 0.47
HPGD P15428 3/20 0.47
ALDH1A1 P00352 3/20 0.47
GFER P55789 1/20 0.47
CTSV O60911 1/20 0.46
CTSL P07711 1/20 0.46
NOTUM Q6P988 1/20 0.45
KDM4E B2RXH2 3/20 0.44
LMNA P02545 2/20 0.44
NQO2 P16083 1/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
POLB P06746 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26128431 0.90 ERCC1 (0.59) ERCC1ERCC4GCGRMAPTHPGD
SCHEMBL18787989 0.87 NOTUM (0.54) GCGRMAPTALDH1A1GFERNOTUM
SCHEMBL1536003 0.84 NOTUM (0.56) MAPTHPGDALDH1A1GFERNOTUM
SCHEMBL7938359 0.79 ALDH1A1 (0.60) ALDH1A1KMT2AMEN1POLB
SCHEMBL412237 0.79 ALDH1A1 (0.60) ALDH1A1KMT2AMEN1POLB
SCHEMBL12444110 0.79 ALDH1A1 (0.60) ALDH1A1KMT2AMEN1POLB
SCHEMBL18952025 0.78 NOTUM (0.46) MAPTHPGDALDH1A1GFERNOTUM
Water SCHEMBL3745867 0.76 ALDH1A1 (0.56) ALDH1A1KMT2AMEN1POLB
Water SCHEMBL6337149 0.76 ALDH1A1 (0.56) ALDH1A1KMT2AMEN1POLB
SCHEMBL11491288 0.76 ALDH1A1 (0.56) ALDH1A1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478591-B A kind of method for splitting of Atorvastatin condensation product intermediate 北京嘉林药业股份有限公司 2018-11-13 CN claimed